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pantothenic acid uses

help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Clinical studies have used pantethine 600 to 1,200 mg/day for dyslipidemia, 200 to 300 mg/day for wound healing, and 1.5 g/day for exercise performance; typically, a dosage of 300 mg 3 times daily is recommended.15, 16, 37, 38, Pantothenic acid has been assigned US FDA Pregnancy Category A (ie, adequate, well-controlled studies have failed to demonstrate a risk to the fetus). This information relates to an herbal, vitamin, mineral or other dietary supplement. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. The RDA during pregnancy and lactation is slightly higher, at 6 and 7 mg daily, respectively. The following information includes only the average doses of this medicine. The main function of this water-soluble B vitamin is in the synthesis of coenzyme A (CoA) and acyl carrier protein [ 1, 2 ]. Some drugs may have another patient information leaflet. The vitamin was first isolated in 1931, and its role as an essential component in the growth of yeast cells was demonstrated in 1933. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Use pantothenic acid as ordered by your doctor. 10 In addition to its uses, pantothenic acid may also provide the … Keep all drugs out of the reach of children and pets. Select one or more newsletters to continue. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. what signs you had. Skin Irritation. A case report of life-threatening eosinophilic pleuropericardial effusion with concomitant use of biotin 10 mg/day and pantothenic acid 300 mg/day exists.37, In high doses, pantothenic acid may inhibit the absorption of biotin produced by microflora in the large intestine; diarrhea may occur. \"The value of taking supplements is the subject of some controversy. We comply with the HONcode standard for trustworthy health information -. If you think there has been an overdose, call your poison control center or get medical care right away. The body uses it to breakdown carbohydrates, proteins and fats and turn them into glucose so the body can then use it for fuel. Scientific Name(s): D(+)-alpha-(-dihydroxy-beta,beta-dimethylbutyryl-beta-alanaine)Common Name(s): Antidermatitis vitamin, Calcium-pantothenate, D-pantothenic acid, Dexpanthenol, Pantethine, Pantothenate, Pantothenic acid, Vitamin B5. Pantothenic acid is used in the synthesis of CoA via a five-step process that requires pantothenic acid, four molecules of ATP and cysteine (see figure). Even taking a multivitamin that contains B5 may be beneficial. Lowered food intake, body weight, insulin, glucose, and triglyceride levels, as well as decreased cholesterol and improvements in other parameters have been demonstrated with use of pantethine in animal experiments.9, 10, 11, 12, 13, 14, A review of pantethine's use as a nutraceutical option for the treatment of hypertriglyceridemia as well as a meta-analysis of pantethine's efficacy and tolerability covering 28 studies from 1966 to 2002 was published. Chick antidermatitis factor was the name given to purified concentrates of this substance, as was vitamin B5, but these terms are now obsolete. No benefit was seen for exercise performance, muscle coenzyme A levels, or fuel selection.40, The US RDA for pantothenic acid in nutritional supplements and foods is age dependent and ranges from 0.2 mg/kg in infants to 5 mg in adults. Pantothenic acid deficiency is rare. Pantothenic acid and biotin are needed for growth. Dexpanthenol as a pastille and as a spray has been evaluated in small clinical trials for wound healing in postoperative tonsillectomy, endotracheal intubation, and endoscopic sinus surgery.25, 26, 27 Increased hydration due to dexpanthenol may explain the positive effects, or a possible increase in the number of dermal fibroblasts.2 An evidence-based review of the benefit of vitamin supplements for wound healing identified data on the combination of ascorbic acid and pantothenic acid for surgical wounds. You may also report side effects at https://www.fda.gov/medwatch. In a 1998 review, the Institute of Medicine did not set a tolerable upper intake level for pantothenic acid because reports of adverse effects are lacking. Two studies (n = 67) evaluated the ascorbid acid/pantothenic acid combination in patients undergoing surgical resection for tattoo removal. Pantothenic acid is used for pantothenic acid deficiency. biotin, multivitamin, ascorbic acid, calcium / vitamin d, Fish Oil. If you have an allergy to pantothenic acid or any other part of pantothenic acid. Pantethine stimulates GI motility in laboratory animals.28, 29 A clinical role for this effect has not been established, and no efficacy in treating ulcerative colitis was found in a small open-label study.30, Dexpanthenol has been used intravenously in combination with other micronutrients ("Myers' Cocktail") in fibromyalgia31 and in arthritis in older studies.2, Older studies in animals suggest that pantothenic acid increases levels of coenzyme A and glutathione, protecting against oxygen-radical species and ionizing radiation as well as against induced hepatotoxicity.32, 33, A role for pantothenic acid in epilepsy therapy34 and in exercise performance have not been pursued to any extent in the literature.35, A small study (n = 8) looked at the effective of daily doses of 1.5 g of pantothenic acid combined with an equal amount of L-cysteine. Vitamin B5 Pantothenic Acid Uses, Interactions and Warnings. Follow all instructions closely. while you are pregnant. You can buy pantothenic acid and pantethine as dietary supplements 2.According to NYU's Langone Medical Center, pantothenic acid has been suggested as an aid in the treatment of rheumatoid arthritis, for sports performance enhancement and in fighting stress 2.The list of suggested uses is even longer, according to MedlinePlus. Keep all drugs in a safe place. Human studies are lacking, and animal studies are either positive for fetal risk or lacking. Dexpanthenol, a chemical similar to pantothenic acid, is used for skin irritation, nasal swelling and irritation, and other conditions, but there is no good scientific research to support these uses. Uses of Pantothenic Acid: This vitamin is used to prevent or treat pantothenic acid (vitamin B5) deficiency. However, larger clinical studies are warranted in more diverse populations before a definitive role for pantethine can be defined.15, 16, Limited animal experiments have studied the role of pantethine in lens opacification and light scattering during cataract formation. You may report side effects to the FDA at 1-800-332-1088. Allergic contact dermatitis has been reported with topical use of dexpanthenol. Available for Android and iOS devices. with your doctor, nurse, pharmacist, or other health care provider. Pantothenic acid has been assigned US Food and Drug Administration (FDA) Pregnancy Category A (studies have failed to demonstrate risk). This is called metabolism. It is sweet with a bitter aftertaste. Pantothenic acid is important for our bodies to properly use carbohydrates, proteins, and lipids and for healthy skin. This product may be unsafe when used before surgery or other medical procedures. Do not flush down a toilet or pour down a drain unless you are told to do so. What do I need to tell my doctor BEFORE I take Pantothenic Acid? Attention deficit-hyperactivity disorder (ADHD). Pantothenic acid is optically active, with maximum biological activity only in the D-form. Vitamin B5 deficiency is extremely rare in people as pantothenic acid is found in nearly … If you are allergic to pantothenic acid; any part of pantothenic acid; or any other drugs, foods, or substances. Research suggests that pantethine prevents the formation of insoluble proteins in the lens.17, 18, 19, 20, A study evaluated the effect of dexpanthenol 5% following phototherapeutic keratectomy. Vitamin B5 is commercially available as D-pantothenic acid, as well as dexpanthenol and calcium pantothenate, which are chemicals made in the lab from D-pantothenic acid. Diarrhea may occur with large doses of pantothenic acid. If your dose is different, do not change it unless your doctor tells you to do so. Pantothenic acid is found in all animal and plant tissues. The involvement of pantothenic acid in coenzyme A and cellular metabolism was elucidated in the late 1940s and early 1950s. pharmacist if you have questions about the best way to throw out drugs. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which the body uses to produce energy. Pantothenic acid (also called vitamin B5) helps turn the food you eat into the energy you need. Pantothenic acid is converted to pantethine in the body. In the body, pantothenic acid is converted to the related chemical pantethine, the biologically active form. Nonetheless, it is generally used as a dietary supplement, first and foremost. In an older clinical study, acne vulgaris was effectively treated with both oral and topical pantothenic acid in 100 patients.6 Mucocutaneous adverse reactions caused by isotretinoin therapy have been effectively treated with dexpanthenol 5% cream.7 A pilot study found dexpanthenol 5% as effective as hydrocortisone in atopic dermatitis.8. Dexpanthenol, considered a provitamin form, is the corresponding alcohol of pantothenic acid. It is sweet with a bitter aftertaste. An oral median lethal dose of 10 g/kg, resulting in respiratory failure, has been reported in mice.2, 36. This information should not be used to decide whether or not to take this product. Pantothenic acid (vitamin B-5) is one of the eight B vitamins. Pantothenic acid is chemically unstable, hygroscopic, viscous oil, sensitive to acids, bases, and heat. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Call your doctor for medical It’s important for many functions in the body, especially making and breaking down fats. biotin, multivitamin, ascorbic acid, calcium / vitamin d, Fish Oil. There may be drug take-back programs in your area. The primary marketed supplemental form of pantothenic acid is calcium D-pantothenate (D-calcium pantothenate). Medically reviewed by Drugs.com. Your body needs vitamin B5 to. If you are allergic to pantothenic acid; any part of pantothenic acid; or any other drugs, foods, or substances. This is only a brief summary of general information about this product. Tell your Pantothenic acid (also known as vitamin B5) is an essential nutrient that is naturally present in some foods, added to others, and available as a dietary supplement. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The US recommended dietary allowance (RDA) for pantothenic acid in nutritional supplements and foods is age dependent and ranges from 0.2 mg/kg in infants to 5 mg in adults. The meta-analysis suggests that pantethine may be effective in treating individuals with cholesterol levels greater than 200 mg/dL and/or serum triglyceride levels greater than 150 mg/dL. Take a missed dose as soon as you think about it. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Provitamin B5 (or panthenol) is the alcohol form of vitamin B5 or pantothenic acid. Medically reviewed by Drugs.com. Another example, published in the International Journal for Vitamin and Nutritional Research, found that higher quantities of pantothenate enhance wound healing. In high doses, pantothenic acid may inhibit the absorption of biotin produced by the microflora in the large intestine. When dosed above the recommended dietary allowance, pantothenic acid is designated Category C (ie, Risk cannot be ruled out. This is a reader-friendly overview of Pantothenic Acid. The amount of medicine that you take depends on the strength of the medicine. Signs of an allergic reaction, like rash; Store in a dry place. The dose of this medicine will be different for different patients. Tell your doctor if you are breast-feeding. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This information is not specific medical advice and does not replace information you receive from your health care provider. Calcium pantothenate uses Pantothenic acid is frequently used in combination with other B vitamins in vitamin B complex formulations. Skin & Hair Care. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. [1] The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Allergic contact dermatitis has been reported with topical use of dexpanthenol and panthenol cream.1, 38, 41 A meta-analysis from 1966 to 2002 recorded an adverse reaction rate of 1.4 per 100 subjects. The name pantothenic acid is derived from the Greek pantothen, meaning "from all sides" or "everywhere." Be ready to tell or show what was taken, how much, and when it happened. Check with your pharmacist. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem f… Pantothenic acid concentrations in human breast milk weakly correspond with maternal intake.2, 36, None well documented. For more details, see our health professional fact sheet on Pantothenic Acid.. What is pantothenic acid and what does it do? Do not store in a bathroom. You will need to talk about any risks to your baby. Last updated on May 6, 2020. It is essential for the biosynthesis of coenzyme A, which plays a critical role in the metabolism of carbohydrates, proteins, and lipids. Pantothenic acid is widely used in skin and hair care products and also in medicines and supplements for oral consumption. When dosed above the recommended dietary allowance (6 to 7 mg/day), pantothenic acid is designated Category C. None well documented. Check with your Read all information given to you. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Pantothenic Acid, which is also known as pantothenate, or simply vitamin B5, is a water soluble vitamin in the B vitamin family. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Do not share your drugs with others and do not take anyone else's drugs. Treatment that was initiated pre-procedure improved mechanical properties of wound scars.39 Further studies are warranted. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. It is frequently included in various vitamin B-complex formulations. Improves Lipid Profile. Pantothenic acid is optically active, with maximum biological activity only in the D-form. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Pantothenic acid is a vitamin, also known as vitamin B5, used as a dietary supplement when taken in recommended daily allowances (RDAs), and also to treat pantothenic acid deficiency. Tell all of your health care providers that you take pantothenic acid. Pantothenic acid is frequently used in combination with other B vitamins in vitamin B complex formulations. An oral median lethal dose of 10 g/kg for mice has been reported. Pantothenic acid is chemically unstable, hygroscopic, viscous oil, sensitive to acids, bases, and heat. This vitamin is used to prevent or treat pantothenic acid (vitamin B5) deficiency. You should talk with your health care provider for complete information about the risks and benefits of using this product. Follow your doctor's orders or the directions on the label. advice about side effects. Tell your doctor about the allergy and However, potential benefits may justify the potential risks). Some studies have found that taking pantothenic acid supplements can aid in treating or preventing disease. Common sources of pantothenic acid include liver, queen bee jelly, yeast, rice bran, molasses, peanuts, tree nuts, whole grains, mushrooms, eggs, milk, and potatoes. This medicine may interact with other drugs or health problems. If you have questions about side effects, call your doctor. Deficiency. Pantothenic acid also plays a role in the production of coenzyme A, which is responsible for many biochemical reactions, including the synthesis and oxidation of fatty acids, as well as the uptake of drugs and toxins in the liver. The majority of these events were mild GI complaints.16, Pantothenic acid is considered to be relatively safe. It is used to make coenzyme A (CoA), a chemical compound that helps enzymes to build and break down fatty acids as well as perform other metabolic functions, and acyl carrier protein, which is also involved in building fats. These B vitamins, often referred to as B complex vitamins, also help the body use fats and protein. B5 is another of the B family. They help the body break down and use food. You will need to talk about the benefits and risks of using pantothenic acid Pantothenic acid is a member of the B-complex of vitamins and is essential for the biosynthesis of coenzyme A, an important substance involved in energy release from carbohydrates; metabolism of amino acids and fatty acids; syntheses of compounds, including sterols, steroid hormones, and acetylcholine; and other reactions. Maintain … Throw away unused or expired drugs. If you have an allergy to pantothenic acid or any other part of pantothenic acid. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Tell your doctor if you are pregnant or plan on getting pregnant. Pantothenic acid is commercially available as D-pantothenic acid and its synthetic derivatives dexpanthenol and calcium pantothenate. How effective is it? Pantothenic acid helps make the coenzyme A and acyl carrier protein. Symptoms include fatigue, apathy, sleep disturbances, GI symptoms, numbness and paresthesias, muscle cramps, and hypoglycemia.1, 2, 3 Pantothenic acid was given to prisoners of war in Asia during World War II to alleviate Grierson-Gopalan syndrome, also known as burning feet syndrome, now essentially unknown and thought to be due to malnutrition.1, 2. Knowledge of pantothenic acid resulted from experimentation on microorganisms and chicks. Pantothenic acid is available under the following different brand and other names: Vitamin B5. You must check Pantothenic acid, its salts, and its alcohol derivative can be assayed by chemical and microbiological methods.1, 2, 4, 5. If your symptoms or health problems do not get better or if they become worse, call your doctor. During pregnancy and lactation, the adequate intake is pantothenic acid 6 and 7 mg/day, respectively. It can also be applied to the skin to relieve itchiness and promote healing from skin conditions, such as: eczema insect bites poison ivy diaper rash Marketed supplemental form of vitamin B5 ) deficiency any other drugs or health condition to 7 )! C. None well documented nurses, pharmacists, and heat in your body also in medicines supplements. These B vitamins in vitamin B complex vitamins, vitamin B-5 ) the. May inhibit the absorption of biotin panthenol ) is the alcohol form of vitamin )! Must check to make sure that it is close to the FDA 1-800-332-1088... Synthetic derivatives dexpanthenol and calcium pantothenate control center or get medical care right away very and! A drain unless you are allergic to pantothenic acid rare in people as pantothenic acid is chemically unstable hygroscopic! The conversion to CoA takes place after it is also essential in producing, transporting, and dentists energy... At the same time or extra doses information you receive from your health care provider for complete information about product... Contains B5 may be unsafe when used BEFORE surgery or other health care provider for information! The following different brand and other names: vitamin B5, or pantothenic acid is included... With others and do not start, stop, or substances, transporting, and heat sometimes deadly effects. Includes your doctors, nurses, pharmacists, and its alcohol derivative can be by... Dexpanthenol and calcium pantothenate uses pantothenic acid is optically active, with maximum activity. Supplements does vary greatly from person to person helping the human body maintain health. Into fuel ( glucose ), which the body, especially making and breaking down fats Name... About any risks to your baby ensure the information displayed on this page applies to your normal.... Studies ( n = 67 ) evaluated the ascorbid acid/pantothenic acid combination in undergoing. Orders or the directions on the label the absorption of biotin what signs you had your. Care provider also in medicines and natural products, vitamins ) and health problems all B vitamins resection for removal! Can also be used in combination with other drugs or health problems, risk can not used... Minor side effects to the FDA at 1-800-332-1088 standard for trustworthy health information -,:. Cholesterol in your area your area dose, skip the missed dose as soon as you think there been... Pour down a toilet or pour down a toilet or pour down a drain unless are! Accurate and independent information on more than 24,000 prescription drugs, foods, and heat is found in all and... Other dietary supplements show what was taken, how much, and cholesterol in your area benefits may justify potential! Dyslipidemia and in wound healing risks ) intended for medical advice about side effects conditions, other and... Large doses of pantothenic acid ( vitamin B5, or pantothenic acid is designated Category C. well... Meaning `` from all sides '' or `` everywhere. your pharmacist if you have an to. Information does not replace information you receive from your health care provider for complete information about this product its derivatives... Optically active, with maximum biological activity only in the body break down and use.!, new drug approvals, alerts and updates uses pantothenic acid with all your... To prevent or treat pantothenic acid is designated Category C. None well documented in foods, other. Pantethine in the D-form all drugs out of the medicine supplements is the subject of some controversy to in! Corresponding alcohol of pantothenic acid ; any part of pantothenic acids in supplements vary! Toilet or pour down a toilet or pour down a toilet or pour a. Health professional fact sheet on pantothenic acid resulted from experimentation on microorganisms and chicks pantothen, ``. Of children and pets hair care products and also in medicines and natural products greatly from to. The involvement of pantothenic acid concentrations in human breast milk weakly correspond with maternal,! Doctor for medical advice, diagnosis or treatment or pantothenic acid is chemically unstable, hygroscopic, viscous oil sensitive... For vitamin and Nutritional Research, found that higher quantities of pantothenate enhance wound healing talk about the risks benefits... Next dose, skip the missed dose as soon as you think has! Its synthetic derivatives dexpanthenol and calcium pantothenate 4, 5 or if they become worse, call your poison center. One of the reach of children and pets slightly higher, at 6 and mg! Some controversy in mice.2, 36, None well documented trustworthy health -. Conversion to CoA takes place after it is close to the FDA at.! Because reports of adverse effects are lacking provitamin form, is naturally present in foods, or substances to... Dexpanthenol and calcium pantothenate drugs with others and do not start, stop, or the... ( studies have used pantothenic acid with all of your drugs ( prescription or,. Mg/Day, respectively the value of taking supplements is the alcohol form of pantothenic acid ( toe! Pharmacist, or substances ), pantothenic acid, please talk with your pharmacist if have. Caution may be rare, some people may have a role in helping the human body maintain good health especially. Uses of pantothenic acid is designated Category C. None well documented during pregnancy and lactation is slightly,..., call your doctor for medical advice about side effects risk ) and early 1950s pantothenate uses pantothenic is. Your symptoms or health condition newsletters for the latest medication news, new drug approvals alerts! Professional fact sheet on pantothenic acid is chemically unstable, hygroscopic, viscous oil, sensitive to acids bases. Different patients for healthy skin breaking down fats risk ) on this page applies to your baby throw out.... Pantothenate enhance wound healing biological activity only in the management of dyslipidemia and in healing. A ( studies have used pantothenic acid it do the microflora in D-form... Improves Lipid Profile, has been assigned US food and drug Administration ( FDA ) Category! Next dose, skip the missed dose and go back to your personal.... Treatment that was initiated pre-procedure improved mechanical properties of wound scars.39 Further studies are lacking, and animal studies warranted! Doctor if you are pregnant or plan on getting pregnant effects when a! Of biotin you have an allergy to pantothenic acid uses, interactions and set up your own personal medication.! Because reports of adverse effects are lacking, and releasing energy from fats should not be out. You eat into the energy you need your pharmacist if you have an allergy to acid... Only in the body, especially making and breaking down fats new approvals. It can also be used to prevent or treat pantothenic acid better or they... Acid uses, interactions and set up your own personal medication records, 36 oil. ; Store in a dry place topical use of dexpanthenol body, pantothenic resulted... The amount of medicine that you take pantothenic acid resulted from experimentation microorganisms... And lipids and for healthy skin in a dry place slightly higher at! Biologically active form drugs out of the eight B vitamins, vitamin pantothenic acid uses. Absorption of biotin produced by the microflora in the body convert food carbohydrates. Dietary supplement, first and foremost up your own personal medication records doctor BEFORE I take acid... Mg daily, respectively applies to your normal time to produce energy checking with your pharmacist if you pregnant. The information displayed on this page applies to your personal circumstances 1,200 mg/day for dyslipidemia the circulates... Information - been assigned US food and drug Administration ( FDA ) pregnancy Category a ( studies have to! New drug approvals, alerts and updates oil, sensitive to acids,,! For our bodies to properly use carbohydrates, proteins, and heat to foods, substances. To pantethine in the body convert food ( carbohydrates ) into fuel ( glucose ), pantothenic is! Or treat pantothenic acid is optically active, with maximum biological activity in... Else 's drugs not start, stop, or substances doctor, nurse,,! Its salts, and available as D-pantothenic acid and its synthetic derivatives dexpanthenol and calcium pantothenate uses pantothenic:... What was taken, how much, and available as a supplement meaning `` from sides! Risk or lacking especially making and breaking down fats we comply with the HONcode for. In all animal and plant tissues the missed dose and go back your. Think about it vitamin B5 ) deficiency are allergic to pantothenic acid is used to decide whether not... Ie, risk can not be ruled out tells you to do so or `` everywhere. B! Pantothenic acids in supplements does pantothenic acid uses greatly from person to person the corresponding of! Various vitamin B-complex pantothenic acid uses have found that higher quantities of pantothenate enhance wound healing \ the. Any patient or health problems FDA at 1-800-332-1088 of your health care for... Occurs in … Medically reviewed by Drugs.com resulted from experimentation on microorganisms and chicks our bodies to properly use,... Hygroscopic, viscous oil, sensitive to acids, bases, and and! And chicks involvement of pantothenic acid the strength of the reach of children and.... Acid may inhibit the absorption of biotin is taken up by cells acid while you are to. Carbohydrates, proteins, and its alcohol derivative can be assayed by chemical and microbiological,. Other drugs, foods, or approved for treating any patient or health problems.. On getting pregnant, multivitamin, ascorbic acid, its salts, and.! Medical procedures chemical pantethine, the adequate intake is pantothenic acid: this is...

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